RNA-dependent RNA polymerase

Definition

RNA-dependent RNA polymerase (RdRp) or RNA replicase is an enzyme that catalyzes the replication of RNA from an RNA template. Specifically, it catalyzes synthesis of the RNA strand complementary to a given RNA template. This is in contrast to typical DNA-dependent RNA polymerases (DdRP), which all organisms use to catalyze the transcription of RNA from a DNA template.

Related concepts

ADP—thymidine kinase Actinomycin D Active site Adenylate kinase Alcohol (chemistry)Allosteric regulation AlphaFold Alpha helix Alternative splicing Antiparallel (biochemistry)Archaeal transcription Archaeal translation Asparagine Aspartate kinase Aspartic acid BRENDA Bacterial transcription Bacterial translation Bacteriophage Beta sheet Binding site Birnaviridae Bunyavirales CAS registry number CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase CDP-diacylglycerol—inositol 3-phosphatidyltransferase CDP-diacylglycerol—serine O-phosphatidyltransferase COVID-19 Caenorhabditis elegans Carboxy Carmovirus Catalysis Catalytic triad Cell membrane Cell surface receptor Central dogma of molecular biology Cis-regulatory element Class II PI 3-kinases Class I PI 3-kinases Cofactor (biochemistry)Complementarity (molecular biology)Complementation (genetics)Conformational change Conserved sequence Cooperativity Coronaviridae Creatine kinase Cystovirus DNA DNA-dependent RNA polymerase DNA dependent RNA polymerase DNA polymerase DNA polymerase I DNA polymerase II DNA polymerase III holoenzyme DNA polymerase IV DNA polymerase V DNA polymerase alpha DNA polymerase beta DNA polymerase delta DNA polymerase epsilon DNA polymerase eta DNA polymerase lambda DNA polymerase mu DNA polymerase nu Deoxycytidine kinase Diacylglycerol kinase Diffusion-limited enzyme Diphosphate Diphosphotransferase Double-stranded RNA Eadie–Hofstee diagram Endocytosis Enzyme Enzyme Commission number Enzyme activator Enzyme catalysis Enzyme inhibitor Enzyme kinetics Enzyme promiscuity Epigenetics Eukaryotes Eukaryotic transcription Eukaryotic translation ExPASy Exoribonuclease Fiersviridae Five-prime cap Flavivirus Food and Drug Administration François Jacob Fructokinase GS-441524 Galactokinase Galactose-1-phosphate uridylyltransferase Gene Ontology Gene expression Gene regulatory network Genetic code Genetic recombination Genomic imprinting Glucokinase Glucose-1,6-bisphosphate synthase Glutamate 5-kinase Glycerol kinase Guanylate kinase Guanylyltransferase Hanes–Woolf plot Hepatic fructokinase Hepatitis C Hepatitis C virus Hexokinase Histidine kinase Histone acetylation and deacetylation Host (biology)Hydrolase Hypoviridae IntEnz Integrase InterPro Introduction to genetics Isomerase Jacques Monod KEGG Kinase Lac operon Leviviridae Ligase Lineweaver–Burk plot List of EC numbers (EC 1)List of EC numbers (EC 2)List of EC numbers (EC 3)List of EC numbers (EC 4)List of EC numbers (EC 5)List of EC numbers (EC 6)List of EC numbers (EC 7)List of enzymes Lyase MRNA capping enzyme Medical Subject Headings Mengovirus Messenger RNA MetaCyc Mevalonate kinase Michaelis–Menten kinetics MicroRNA Mononegavirales Murine respirovirus Mutation rate N-acetylglucosamine-1-phosphate transferase NAD+ kinase NS5B NS5B inhibitor National Center for Biotechnology Information Neurospora crassa Nitrogen Nucleoside-diphosphate kinase Nucleoside analogue Nucleoside monophosphate Nucleoside triphosphate Nucleotide Nucleotidyltransferase Oligomer Orthomyxoviridae Oxidoreductase Oxyanion hole P-bodies PFKL PFKM PFKP PFP (enzyme)POLG POLI POLK POLQ POLRMT PRIAM enzyme-specific profiles PRIM1 PRIM2 Pantothenate kinase Paramecium Partitiviridae Pestivirus Pfam Pfu DNA polymerase Phosphate Phosphatidylcholine synthase Phosphodiester bond Phosphofructokinase Phosphofructokinase 1 Phosphofructokinase 2 Phosphoglycerate kinase Phosphoinositide 3-kinase Phosphomevalonate kinase Phosphorolysis Phosphorus Phosphorylation Phosphotransferase Plants Poliovirus Polyadenylation Polymerase Polynucleotide adenylyltransferase Polynucleotide phosphorylase Polyprotein Positive-sense single-stranded RNA virus Post-transcriptional modification Post-transcriptional regulation Post-translational modification Post-translational regulation PrimPol Primary transcript Primase Primer (molecular biology)Prion Promoter (genetics)Proofreading (biology)Protein Protein-histidine pros-kinase Protein-histidine tele-kinase Protein Data Bank Protein family Protein kinase Protein superfamily Protein trimer Proteolysis Pyruvate kinase REV3L RNA RNA-induced silencing complex RNA interference RNA polymerase RNA polymerase I RNA polymerase II RNA polymerase III RNA polymerase IV RNA polymerase V RNA splicing RNA virus RNase PH Recombinase Regulation of gene expression Remdesivir Reoviridae Retrovirus Reverse transcriptase Reverse transcription Ribavirin Riboflavin kinase Ribonucleoside Ribose-phosphate diphosphokinase Ribosome Ribosome-nascent chain complex Self-replication Sequence motif Serine/threonine-specific protein kinase Shikimate kinase Small interfering RNA Small temporal RNA Sofosbuvir Sphingosine kinase Spiegelman's Monster Structural Classification of Proteins T7 DNA polymerase T7 RNA polymerase Taq polymerase Telomerase Terminal deoxynucleotidyl transferase Thiamine-diphosphate kinase Thiamine diphosphokinase Thymidine kinase Tombusvirus Totiviridae Transcription (biology)Transcription (genetics)Transcription factor Transcriptional regulation Transfer RNA Transferase Translation (biology)Translational regulation Translocase Transposase Tyrosine kinase UMP kinase UTP—glucose-1-phosphate uridylyltransferase VPg Vesicular stomatitis virus Viral genome Virus

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