Reverse transcriptase

Definition

A reverse transcriptase (RT) is an enzyme that uses an RNA molecule as a template to synthesize a complementary DNA molecule, through a process termed reverse transcription. Reverse transcriptases are used by viruses such as HIV and hepatitis B to replicate their genomes, by retrotransposon mobile genetic elements to proliferate within the host genome, and by eukaryotic cells to extend the telomeres at the ends of their linear chromosomes. The process does not violate the flows of genetic information as described by the classical central dogma, but rather expands it to include transfers of information from RNA to DNA.

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RNA-dependent RNA polymerase RNA polymerase RNA polymerase I RNA polymerase II RNA polymerase III RNA polymerase IV RNA polymerase V RNA sequencing RNA virus RNAse H RNase H RNase PH Recombinase Renato Dulbecco Resistance to antiviral drugs Respiratory syncytial virus G protein Retron Retrotransposon Retrotransposon marker Retrovirus Retroviruses Rev (HIV)Reverse-transcriptase inhibitor Reverse transcribing virus (disambiguation)Reverse transcription polymerase chain reaction Rhinovirus Riboflavin kinase Ribonuclease Ribonuclease H Ribose-phosphate diphosphokinase Riboviria Rotavirus Rous sarcoma virus SARS-CoV-2 SV40 SV40 large T antigen Sense (molecular biology)Serine/threonine-specific protein kinase Shikimate kinase Single-nucleotide polymorphism Small tumor antigen Sphingosine kinase SsRNA-RT Structural Classification of Proteins Structure and genome of HIV T7 DNA polymerase T7 RNA polymerase TRNA Taq polymerase Tat (HIV)Telomerase Telomerase reverse transcriptase Telomere 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