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MicroRNA

Definition

Micro ribonucleic acid are small, single-stranded, non-coding RNA molecules containing 21–23 nucleotides. Found in plants, animals, and even some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. miRNAs base-pair to complementary sequences in messenger RNA (mRNA) molecules, then silence said mRNA molecules by one or more of the following processes:Cleaving the mRNA strand into two pieces. Destabilizing the mRNA by shortening its poly(A) tail. Reducing translation of the mRNA into proteins.

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3' UTR 5' cap ARID3A AT hook AU-rich element Abiogenesis Abiotic stress Accumbens Addiction Adenosine Adenosine deaminase Adenosine monophosphate Adipocyte Adipogenesis Aging Alcohol dependence Alcohol withdrawal syndrome Alcoholism Alpha helix Alu sequence Alzheimer's disease Anastasia Khvorova Animal Annual Review of Genetics Antagomir Anti-miRNA oligonucleotides Antisense Antisense RNA Anxiety disorder Apoptosis Arabidopsis thaliana Argonaute Arteriole Arthropod Artificially Expanded Genetic Information System Atherosclerosis B-cell chronic lymphocytic leukemia B-cell receptor BCL2-like 1 (gene)BDNF Bacterial artificial chromosome Basal forebrain Base-pair Bcl-2-associated X protein Biomarker Bipolar disorder Bona fide Bone marrow Brown algae C-terminal C19MC miRNA cluster CEBPA CRISPR Caenorhabditis elegans Calcium metabolism Cardiomyopathy Carlo M. Croce Causality CeRNA Cell (journal)Cell adhesion Cell cycle Cell proliferation Cell signaling Cerebrospinal fluid Chronic lymphocytic leukemia Circadian rhythm Cis-natural antisense transcript Cloning vector Collagen Colon cancer Colorectal cancer Complementarity (molecular biology)Complementary DNA Computerized tomography Conserved sequence Cosmid CpG site Cytoplasm DGCR8 DNA DNA methylation DNA mismatch repair DNA repair DNA replication Deadenylation Decision making Deoxyribonucleotide Deoxyribozyme DiGeorge Syndrome Diabetes Dicer Dicer-like1 Dopamine receptor D1 Double-stranded RNA Drosha Drosophila ERCC1 Ectopic expression Elastin Elizabeth Murchison Endoplasmic reticulum Enhancer RNA Enzyme Epigenetic methylation Epilepsy Eukaryotic translation Evolutionarily conserved Exon Exoribonuclease Extracellular RNA FOXD1 Feed forward (control)Fluorescent-activated cell sorting Forebrain FosB Fosmid Fragile X syndrome G-quadruplex Gary Ruvkun Gene expression Gene silencing Genes & Development Genome Genomic DNA Germline Glioblastomas Glycol nucleic acid Granulocyte macrophage colony-stimulating factor Gregory Hannon Guanosine triphosphate Guide RNA HMGA Helicase Hemostasis Hepatitis C Hexose Histone Hodgkin lymphoma Host–pathogen interaction Hua-Enhancer1 Human artificial chromosome Human genome Human herpesvirus-6 Huntington's disease In silico Inflammatory cytokine Inosine Insulin resistance Interferon Internal ribosome entry site Internal transcribed spacer Intron Inversely correlated Invertebrates Ischemic stroke Isomir Karyopherin Laboratory mouse Lambda phage Let-7 microRNA precursor Lin-14 Lin-4 microRNA precursor List of RNA structure prediction software List of RNAs Locked nucleic acid Long non-coding RNA Lsy-6 microRNA MIR141 MIR222 MIRN21 MLH1 MMP2 MOV10 MRNA Major depressive disorder Mammalian wide interspersed repeat Manchester University Matrix metalloproteinase Meristem Mesangium Messenger RNA Messenger rna Metalloproteinase Metastasis Methyltransferase MiR-122 MiR-132 MiR-134 MiR-137 MiR-138 MiR-144 MiR-146 MiR-150 MiR-155 MiR-183/96/182 MiR-191 MiR-203 MiR-206 MiR-208 MiR-212 MiR-214 MiR-218 microRNA precursor family MiR-224 MiR-296 MiR-324-5p MiR-33 MiR-338 MiR-9 MiR156 microRNA precursor family MiR160 microRNA precursor family MiR166 microRNA precursor family MiR172 microRNA precursor family MiR390 microRNA precursor family MiR394 microRNA precursor family MiR395 microRNA precursor family MiR396 microRNA precursor family MiR397 microRNA precursor family MiR398 microRNA precursor family MiR399 microRNA precursor family MiR403 microRNA precursor family MiR408 microRNA precursor family MiR444 microRNA precursor family MiR529 microRNA precursor family MiR535 microRNA precursor family MiRNEST MicroDNA MicroRNA 203a MicroRNA Biosensors MicroRNA Sequencing Microarray Microglia Microprocessor complex Mir-101 microRNA precursor family Mir-103/107 microRNA precursor Mir-10 microRNA precursor family Mir-11 microRNA precursor family Mir-124 microRNA precursor family Mir-126 Mir-127 Mir-129 microRNA precursor family Mir-130 microRNA precursor family Mir-133 microRNA precursor family Mir-135 microRNA precursor family Mir-143 Mir-145 Mir-148/mir-152 microRNA precursor family Mir-14 microRNA precursor family Mir-153 microRNA precursor family Mir-154 microRNA precursor family Mir-15 microRNA precursor family Mir-16 microRNA precursor family Mir-17 microRNA precursor family Mir-181 microRNA precursor Mir-184 Mir-185 microRNA precursor family Mir-186 microRNA precursor family Mir-187 microRNA precursor family Mir-188 microRNA precursor family Mir-190 microRNA precursor family Mir-192/215 microRNA precursor Mir-193 microRNA precursor family Mir-194 microRNA precursor family Mir-196 microRNA precursor family Mir-198 microRNA precursor family Mir-199 microRNA precursor Mir-19 microRNA precursor family Mir-1 microRNA precursor family Mir-200 Mir-202 microRNA precursor family Mir-205 Mir-210 microRNA Mir-216 microRNA precursor family Mir-219 microRNA precursor family Mir-22 Mir-221 microRNA Mir-223 Mir-23 microRNA precursor family Mir-241 microRNA precursor family Mir-24 microRNA precursor family Mir-25 microRNA precursor family Mir-26 microRNA precursor family Mir-275 microRNA precursor family Mir-277 microRNA precursor family Mir-278 microRNA precursor family Mir-279 microRNA precursor family Mir-281 microRNA precursor family Mir-282 microRNA precursor family Mir-28 microRNA precursor family Mir-299 microRNA precursor family Mir-29 microRNA precursor Mir-2 microRNA precursor Mir-301 microRNA precursor family Mir-305 microRNA precursor family Mir-30 microRNA precursor Mir-31 Mir-3180 microRNA precursor family Mir-322 microRNA precursor family Mir-326 microRNA precursor family Mir-32 microRNA precursor family Mir-330 microRNA precursor family Mir-331 microRNA precursor family Mir-337 microRNA precursor family Mir-339 microRNA precursor family Mir-340 microRNA precursor family Mir-344 microRNA precursor family Mir-345 microRNA precursor family Mir-346 microRNA precursor family Mir-34 microRNA precursor family Mir-350 microRNA precursor family Mir-351 microRNA precursor family Mir-361 microRNA precursor family Mir-363 microRNA precursor family Mir-365 microRNA precursor family Mir-367 microRNA precursor family Mir-370 microRNA precursor family Mir-374 microRNA precursor family Mir-383 microRNA precursor family Mir-384 microRNA precursor family Mir-3 microRNA precursor family Mir-423 microRNA precursor family Mir-425 microRNA precursor family Mir-42 microRNA precursor family Mir-430 microRNA precursor family Mir-431 microRNA precursor family Mir-432 microRNA precursor family Mir-433 Mir-434 microRNA precursor family Mir-448 microRNA precursor family Mir-449 microRNA precursor family Mir-451 microRNA Mir-452 microRNA precursor family Mir-454 microRNA precursor family Mir-455 microRNA precursor family Mir-46/mir-47/mir-281 microRNA precursor family Mir-474 microRNA precursor family Mir-48 Mir-484 microRNA precursor family Mir-488 microRNA precursor family Mir-489 microRNA precursor family Mir-491 microRNA precursor family Mir-492 microRNA precursor family Mir-497 microRNA precursor family Mir-498 microRNA precursor family Mir-500 microRNA precursor family Mir-503 microRNA precursor family Mir-504 microRNA precursor family Mir-505 microRNA precursor family Mir-506 microRNA precursor family Mir-52 microRNA precursor family Mir-541 microRNA precursor family Mir-542 microRNA precursor family Mir-544 microRNA precursor family Mir-548 microRNA precursor family Mir-549 microRNA precursor family Mir-550 microRNA precursor family Mir-552 microRNA precursor family Mir-558 microRNA precursor family Mir-562 microRNA precursor family Mir-569 microRNA precursor family Mir-572 microRNA precursor family Mir-575 microRNA precursor family Mir-580 microRNA precursor family Mir-584 microRNA precursor family Mir-589 microRNA precursor family Mir-58 microRNA precursor family Mir-590 microRNA precursor family Mir-592 microRNA precursor family Mir-598 microRNA precursor family Mir-5 microRNA precursor family Mir-601 microRNA precursor family Mir-605 microRNA precursor family Mir-612 microRNA precursor family Mir-615 microRNA precursor family Mir-616 microRNA precursor family Mir-618 microRNA precursor family Mir-61 microRNA precursor family Mir-624 microRNA precursor family Mir-625 microRNA precursor family Mir-62 microRNA precursor family Mir-632 microRNA precursor family Mir-633 microRNA precursor family Mir-636 microRNA precursor family Mir-638 microRNA precursor family Mir-650 microRNA precursor family Mir-652 microRNA precursor family Mir-657 microRNA precursor family Mir-661 microRNA precursor family Mir-663 microRNA precursor family Mir-671 microRNA precursor family Mir-672 microRNA precursor family Mir-675 microRNA precursor family Mir-67 microRNA precursor family Mir-6 microRNA precursor Mir-708 microRNA precursor family Mir-711 microRNA precursor family Mir-71 microRNA precursor family Mir-720 microRNA precursor family Mir-744 microRNA precursor family Mir-764 microRNA precursor family Mir-765 microRNA precursor family Mir-767 microRNA precursor family Mir-786 microRNA precursor family Mir-7 microRNA precursor Mir-8/mir-141/mir-200 microRNA precursor family Mir-802 microRNA precursor family Mir-824 microRNA precursor family Mir-828 microRNA precursor family Mir-84 microRNA precursor family Mir-854 microRNA precursor family Mir-872 microRNA precursor family Mir-873 microRNA precursor family Mir-874 microRNA precursor family Mir-885 microRNA precursor family Mir-9/mir-79 microRNA precursor family Mir-92 microRNA precursor family Mir-938 microRNA precursor family Mir-939 microRNA precursor family Mir-96 microRNA Mir-BART1 microRNA precursor family Mir-BART2 microRNA precursor family Mir-BHRF1-1 microRNA precursor family Mir-BHRF1-2 microRNA precursor family Mir-BHRF1-3 microRNA precursor family Mir-M7 microRNA precursor family MirGeneDB Mirtrons Mitochondrial DNA Mnemiopsis leidyi Morpholino Morpholino nucleic acid Multicopy single-stranded DNA Murine Mutation Nematode Nephrology Nervous system Neural development Neurodegeneration Neuroinflammation Nobel Prize in Physiology or Medicine Non-coding DNA Non-coding RNA Non-small-cell lung carcinoma Nucleic Acids Research Nucleic acid Nucleic acid analogue Nucleoside Nucleoside-modified messenger RNA Nucleotide Nucleotide base Nucleus accumbens O-6-methylguanine-DNA methyltransferase Obesity Oligonucleotide Oncogene Oncomir Organellar DNA P-bodies P1-derived artificial chromosome P21 P53 PPARγ Parkinson's disease Pasha (protein)Paywall Peking University Peptide nucleic acid Phagemid Pharmaceutical drug Phosphorothioate nucleic acid Phylogenetics Piwi Piwi-interacting RNA Placozoa Plant Plant development Plasmid Plastid DNA Pluripotent stem cells Polyadenylation Polymerase chain reaction Polypeptides Positron emission tomography Post-transcriptional regulation Prefrontal cortex Primary transcript Promoter (biology)Protein Data Bank Protein kinase Pseudogene Quantitative PCR RNA RNA-induced silencing complex RNA activation RNA editing RNA interference RNA polymerase II RNA polymerase III RNA silencing RNA splicing RNA virus RNase MRP RNase P RT-PCR Ran-GTP Ran (biology)RasiRNA Regulation of gene expression Renin Retrotransposon Retrovirus Reward system Ribonuclease Ribonuclease H Ribonuclease III Ribosomal RNA Riboswitch Ribozyme SECIS element Schizophrenia SciTech (magazine)Science (journal)Scientific American Sequence homology Short hairpin RNA Signal recognition particle RNA Small Cajal body-specific RNA Small activating RNA Small interfering RNA Small nuclear RNA Small nucleolar RNA Small nucleolar RNA-derived microRNA Small temporal RNA Stem-loop Stem cell Striatum Stromal cell Subgenomic mRNA Synaptic plasticity Synaptogenesis TARBP2 TNRC6B TP53INP1 Telomerase RNA component Three prime untranslated region Threose nucleic acid Tissue (biology)Trans-acting siRNA Transcription factors Transcriptome Transfer-messenger RNA Transfer RNA Translation (biology)Trichoplax adhaerens Tumor necrosis factor alpha UTP—glucose-1-phosphate uridylyltransferase Uracil Vault RNA Victor Ambros Viral disease Viroid Virus X-ray crystallography XPO5 XRN2 Xeno nucleic acid Y RNA Yeast artificial chromosome Zinc

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