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Immune system

Definition

The immune system is a network of biological systems that protects an organism from diseases. It detects and responds to a wide variety of pathogens, such as viruses, bacteria, and parasites, as well as cancer cells and foreign objects, such as wood splinters—distinguishing them from the organism's own healthy tissue. Many species have two major subsystems of the immune system. The innate immune system provides a preconfigured response to broad groups of situations and stimuli. The adaptive immune system provides a tailored response to each stimulus by learning to recognize molecules it has previously encountered. Both use molecules and cells to perform their functions.

Related concepts

AIDSAcademic PressAcidActive immunizationAcupunctureAdaptive immune systemAdaptive immunityAdrenal glandAdverse effectAffinity maturationAgnathaAlcohol abuseAllergenAllergyAlloimmunityAllotype (immunology)Alternative medicineAmino acidAmphibianAnal cancerAnaphylaxisAnatomical terminologyAndrogenAnimalAnti-inflammatoryAntibodyAntigenAntigen-antibody reactionAntigen-presenting cellAntigen presentationAntigen processingAntigenic variationAntimicrobial peptidesAntisepticAntiviral drugApoptosisAppendix (anatomy)ArchaeaArteryArthur M. SilversteinAsthmaAutoantibodyAutoimmune diseaseAutoimmune diseasesAutoimmune disorderAutoimmunityAxolotlAzathioprineB-cell receptorB cellBacillus anthracisBacteriaBacteriophageBasophilBasophil granulocyteBiliary tractBiochemical cascadeBiofilmBioinformaticsBiological life cycleBiological systemsBiological tissueBloodBlood plasmaBlood vesselBoneBone marrowBreastBreast milkBronchusBurkholderia cenocepaciaC-type lectinCD154CD16CD19CD1d receptorCD22CD23CD32CD3DCD3GCD3 (immunology)CD3 zetaCD4CD64 (biology)CD79CD79ACD79BCD8CD81CD8 alphaCD8 betaCRISPRCancerCancer immunologyCancer immunotherapyCarbohydrateCarcinogenesisCarpal bonesCartilageCartilaginous jointCatalysisCatecholamineCell-mediated immunityCell differentiationCell divisionCell growthCell membraneCell signalingCell surface receptorCenter for InquiryCentral obesityCentral toleranceCephalochordateCervical cancerCharles JanewayChemokineChemotaxisChemotherapyChiropracticChronic granulomatous diseaseCircadian rhythmCirculatory systemClavicleClonal anergyClonal deletionClonal selectionCo-receptorCo-stimulationColostrumCommensalismCommon lymphoid progenitorComplement membrane attack complexComplement receptor 2Complement systemConformational epitopeConnective tissueConstantly dividing cellsContact dermatitisCords of BillrothCortisolCritical Reviews in ImmunologyCross-reactivityCyclosporinCystic fibrosisCytokineCytokine receptorCytokinesCytolysinCytotoxic T cellCytotoxicityCésar MilsteinDalton (unit)Damage-associated molecular patternsDefensinDendriteDendritic cellDeuterostomeDeveloped countryDeveloping countryDexamethasoneDiabetes mellitus type 1DiseasesDrosophila melanogasterEarEchinodermEggshellEicosanoidElie MetchnikoffEmbryogenesisEndocrine systemEndothelial cellEnzymeEosinophilEosinophil granulocyteEpinephrineEpitheliumEpitopeEsophagusEukaryoteExoskeletonFCARFc receptorFcα/μRFcεRIFemale reproductive systemFemale sex hormonesFemurFetusFeverFibrous jointFibulaFoodborne illnessFoundational Model of AnatomyGamma/delta T cellsGamma delta T cellGastric acidGastrointestinal tractGeneGenetic diseaseGenetic disorderGenitourinary systemGeorges J. F. KöhlerGerm theory of diseaseGerminal centerGlucocorticoidGlymphatic systemGnathostomataGranulocyteGranulysinGrowth factorGrowth hormoneGrowth hormone 1Gut-associated lymphoid tissueGut floraHIVHaematopoietic systemHagfishHaptenHarriet HallHashimoto's thyroiditisHassall's corpusclesHeartHematopoietic stem cellHemichordateHigh endothelial venulesHistory of immunologyHomeopathyHormoneHuman anusHuman bodyHuman brainHuman digestive systemHuman eyeHuman leukocyte antigenHuman mouthHuman musculoskeletal systemHuman noseHuman papillomavirusHuman penisHuman reproductive systemHuman skeletonHuman skinHuman toothHumerusHumoral immune responseHumoral immunityHydrophileHydrophobeHyperglycemiaHypersensitive responseHypersensitivityIFN-gammaIdiotypeImmune-mediated inflammatory diseasesImmune complexImmune network theoryImmune privilegeImmune receptorImmune system contribution to regenerationImmune toleranceImmune tolerance in pregnancyImmunity (medical)ImmunizationImmunodeficiencyImmunogenImmunogeneticsImmunogenicityImmunoglobulinImmunoglobulin AImmunoglobulin EImmunoglobulin GImmunoglobulin MImmunoglobulin class switchingImmunoglobulin superfamilyImmunoinformaticsImmunologic adjuvantImmunological memoryImmunologyImmunomodulatorsImmunoproteomicsImmunosenescenceImmunostimulantImmunostimulatorImmunosuppressiveImmunosuppressive drugImmunosuppressive drugsImmunotherapyInfectionInfectious diseaseInflammasomeInflammationInnate immune systemInnate immunityInnate lymphoid cellInstitute of MedicineInsult (medical)Integumentary systemInterferonInterleukinInterleukin-1Interleukin-12IntestineIntracellularIntravenous immunoglobulinInvertebrateIodineIonIrritationIsotype (immunology)Jawed vertebrateJawed vertebratesJointJunctional diversityKIR2DL1KIR2DL2KIR2DL3KIR2DL4KIR2DL5AKIR2DL5BKIR2DS1KIR2DS2KIR2DS3KIR2DS4KIR2DS5KIR3DL1KIR3DL2KIR3DL3KIR3DS1KidneyKiller-cell immunoglobulin-like receptorKiller T cellsKoch's postulatesLILRA1LILRA2LILRA3LILRA4LILRA5LILRA6LILRB1LILRB2LILRB3LILRB4LILRB5LampreyLarge intestineLarynxLckLeft shift (medicine)LeishmaniaLeishmaniasisLeptinLeucine-rich repeatLeukocyte immunoglobulin-like receptorsLeukocytesLeukotrieneLigandLinear epitopeLingual tonsilsLipList of human cell typesLiverLouis PasteurLungLupus erythematosusLymph nodeLymphatic systemLymphatic vesselLymphocyteLymphokineLymphopoiesisLysisLysosomeLysozymeMHC class IMHC class IIMachine learningMacrophageMajor histocompatibility complexMalariaMale reproductive systemMalnutritionMammalMammary glandMandibleMantle zoneMarginal zoneMast cellMedical Subject HeadingsMedicineMelanocyteMelanomaMenarcheMetacarpal bonesMetastasisMetatarsal bonesMethotrexateMiasma theory of diseaseMicroantibodyMicrobeMicroorganismMimotopeMoleculeMonoclonal antibodyMonocyteMucosa-associated lymphoid tissueMucous membraneMucusMuhammad ibn Zakariya al-RaziMuscleMuscular systemMutationMycobacterium tuberculosisMyeloidMyogenesisNFIL3NOD-like receptorNational Institute of Allergy and Infectious DiseasesNatural killer T cellNatural killer cellNatural killer cellsNeonatal Fc receptorNerveNervous systemNervous tissueNeuroimmune systemNeuronNeutralizing antibodiesNeutrophilNeutrophiliaNeutrophilsNiels Kaj JerneNobel Prize in Physiology or MedicineNon-cellular lifeNon-peptidic antigenNon-rapid eye movement sleepNorepinephrineNutrientObesityOld ageOncogeneOncogenicOpsoninOrgan (biology)Organ transplantOrganismOriginal antigenic sinOropharynxOssiclesOsteichthyesOsteoporosisOvaryOxidative stressPHPaclitaxelPalatine tonsilPancreasPancreatic isletsParasitismParathyroid glandParatopePassive immunizationPatellaPathogenPathogen-associated molecular patternsPathogenesisPathogensPattern recognition receptorPattern recognition receptorsPaul EhrlichPelvisPenis cancerPeptidePeptostreptococcusPerforinPeriarteriolar lymphoid sheathsPeripheral tolerancePeyer's patchPhagocytePhagocytosisPhagolysosomePhagosomePhalanx bonePharyngeal tonsilPharynxPhospholipase A2Pierre Louis MaupertuisPineal glandPituitary glandPlacentaPlague of AthensPlant cuticlePlant disease resistancePlasma cellsPlasmodiumPlateletPolyclonal B cell responsePolyclonal antibodiesPolyclonal responsePolymeric immunoglobulin receptorPositive feedbackPrimary immunodeficiencyPrimary lymphoid organsProkaryoteProlactinProstaglandinProstateProteinProtein biosynthesisProteolysisProteomicsProtistPseudomonas aeruginosaPubertyPublic domainRIG-I-like receptorRNA interferenceRadical (chemistry)Radius (bone)Rapid eye movement sleepRecombination activating geneRectumRed blood cellRed pulpRegeneration (biology)Regulatory T cellRegulatory T cellsRespiratory burstRespiratory systemRespiratory tractRestriction modification systemRheumatoid arthritisRibRibonucleaseRobert KochRomanowsky stainSalivaSalivary glandSalmonellaScanning electron microscopeScrotumSecondary lymphoid organsSecretionSelf-proteinSemenSeminal vesicleSensory systemSevere combined immunodeficiencySherwood GorbachSide-chain theorySignal transductionSkeptical InquirerSkinSkullSleep deprivationSlow-wave sleepSmall intestineSmallpoxSomatic hypermutationSomatic nervous systemSpecific immunitySpinal cordSpleenSplenic hilumSplinterStaphylococcus aureusSternumStomachStreptococcusSubcutaneous tissueSuperantigenSynovial jointSystemic acquired resistanceSystemic lupus erythematosusT-cell depletionT-cell receptorT-cell surface glycoprotein CD3 epsilon chainTCR zetaTGF betaTNF-alphaTRA@TRB@TRD@TRG@T cellT helper cellTarsus (skeleton)TearsTendonTesticleTestosteroneTh1 cellThoracic diaphragmThucydidesThymusThyroidTibiaTissue (biology)Toll-like receptorTongueTonsilTonsillar cryptsToxinTrabeculae of spleenTrabecular arteriesTrabecular veinsTracheaTraining setTransmembrane proteinTransplant rejectionTrypanosoma bruceiTubal tonsilTumorTumor antigenTumor immunologyTumor necrosis factor-αTumor necrosis factor alphaType III secretion systemType II secretion systemTyrosinaseUlnaUreterUrethraUrinary bladderUrinary systemUrineUrochordateUterusV(D)J recombinationVaccinationVaccineVaginaVaginal cancerVariable lymphocyte receptorVascular permeabilityVasodilationVasodilatorVeinVertebral columnVertebrateVertebratesVesicle (biology)Viral envelopeVirusVirus replicationVitamin DVulvaVulva cancerWaldeyer's tonsillar ringWalter ReedWhite blood cellWhite pulpWorld Health OrganizationYellow feverZeta chainZincΒ-adrenergic receptor

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