Definition
Synthetic biological circuits are an application of synthetic biology where biological parts inside a cell are designed to perform logical functions mimicking those observed in electronic circuits. Typically, these circuits are categorized as either genetic circuits, RNA circuits, or protein circuits, depending on the types of biomolecule that interact to create the circuit's behavior. The applications of all three types of circuit range from simply inducing production to adding a measurable element, like green fluorescent protein, to an existing natural biological circuit, to implementing completely new systems of many parts.
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AND gateArtificial cellArtificial gene synthesisBioBrickBiological machineBiomoleculeBiotechnologyBoston UniversityCRISPRCell (biology)CytosolDiauxieDo-it-yourself biologyE. coliElectronic circuitEnzymeExogenousExpanded genetic codeFrancois JacobGalactoseGene regulatory networkGene therapyGenomeGenome editingGlucoseGreen fluorescent proteinHazards of synthetic biologyIPTGJacques MonodJames Collins (bioengineer)Julius LucksLac operonLactoseMetabolic engineeringMichael ElowitzMirror lifeMycoplasma laboratoriumNature (journal)Negated AND gateNegative feedbackNucleic acid analogueOR gateOpen synthetic biologyPlasmidPromoter (genetics)ProteinsProtocellRecombinant DNARegistry of Standard Biological PartsRegulation of gene expressionRepressilatorRepressorRibosomeRibosome binding siteStanislas LeiblerSynthetic biologySynthetic chemistrySynthetic gene databaseSynthetic genomicsSynthetic immunologySystems biologyUnnatural base pairXeno nucleic acidXenobiologyΒ-galactosidase
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