Definition
The coding region of a gene, also known as the coding DNA sequence (CDS), is the portion of a gene's DNA or RNA that codes for a protein. Studying the length, composition, regulation, splicing, structures, and functions of coding regions compared to non-coding regions over different species and time periods can provide a significant amount of important information regarding gene organization and evolution of prokaryotes and eukaryotes. This can further assist in mapping the human genome and developing gene therapy.
Related concepts
AlkylAlkylationAmino acidCarcinogenCoding strandCodonsConserved sequenceDNADNA mismatch repairDNA polymeraseDNA replicationDe novo mutationDegeneracy (biology)Deletion (genetics)Developmental disorderEukaryoteExomeExonFertilisationFive-prime capFive prime untranslated regionFrameshift mutationGC-contentG bandingGeneGene predictionGene silencingGene structureGermline mutationGiemsa-stainHeredityHuman Genome ProjectHuman genomeInfantile epileptic encephalopathyInsertion mutationJunk DNAKaryotypeMRNAMature mRNAMature messenger RNAMissense mutationMutagenMutationNatural selectionNested geneNon-coding DNANon-coding RNANon-coding regionNonsense mutationNucleic acidNucleotideOpen reading frameOpen reading framesOverlapping genePoint mutationPoly a tailPolypeptidePrimary transcriptProkaryotePromoter (genetics)Proofreading (biology)ProteinPurifying selectionRNARNA PolymeraseRNA splicingRegulation of gene expressionRegulatory sequenceRibosomeSequence alignmentSilent mutationSomatic mutationSplice siteSpliceosomeStop codonTemplate strandThree prime untranslated regionThymineTranscription (biology)Transfer RNATransition (genetics)Translation (biology)TransversionUltravioletUntranslated regionUracilWalter GilbertWobble hypothesis
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