Heme

Definition

Heme, or haem, is a ring-shaped iron-containing molecule that serves as a ligand of various proteins, especially as a component of hemoglobin, which carries oxygen in the bloodstream. It is composed of four pyrrole rings with two vinyl and two propionic acid side chains. Heme is biosynthesized in both the bone marrow and the liver.

Related concepts

3'-Phosphoadenosine-5'-phosphosulfate 5,10-Methylenetetrahydrofolate ALAD ALAS1 ALAS2 Acidity Acute intermittent porphyria Adenosine triphosphate Adenosylcobalamin Albumin American English American Institute for Cancer Research Amino acid Aminolevulinic acid Ancient Greek language Aspartyl BMC Cancer Bacteria Bacteriochlorin Bacteriochlorophyll a Bacteriochlorophyll c Bile Bilin (biochemistry)Bilirubin Bilirubin diglucuronide Bilirubin glucuronide Bilirubin metabolism Biliverdin Biliverdin reductase Binding affinity Biologically Biosynthesized Biotin Blood Bloodstream Bohr effect Bone marrow Breast cancer Bromide Calcium Carbon dioxide Carbon monoxide Carbonic acid Catalase Catalysis Chemical mechanism Chloride Chlorin Chlorophyll Chlorophyll a Chlorophyll b Chlorophyll c Chlorophyllide Chlorophyllide a Chlorophyllide b Citric acid cycle Cobalamin Cobalamin biosynthesis Coenzyme A Coenzyme B Coenzyme F420 Coenzyme M Coenzyme Q10 Cofactor (biochemistry)Cofactor F430 Colorectal cancer Commonwealth English Conformational change Congenital erythropoetic porphyria Coordination complex Copper Coproporphyrinogen I Coproporphyrinogen III Coproporphyrinogen III oxidase Coproporphyrinogens Corphin Corrinoid Cyanobacteria Cyanocobalamin Cysteine Cytidine triphosphate Cytochrome Cytochrome P450 Cytochrome c oxidase Cytoplasm Decarboxylase Dehydratase Detoxification Diatomic Dihydrofolic acid Drug metabolism Electron carrier Electron transfer Electron transfer chain Emopexin Endothelial NOS Enzyme Eosinophil peroxidase Eric L. Hegg Erythrocytes Erythropoietic protoporphyria Ester bond Farnesene Feces Fenton's reagent Ferrochelatase Ferrous Flavin adenine dinucleotide Flavin mononucleotide Formaldehyde Formyl Free radical Globin Glucuronic acid Glucuronosyltransferase Glutamyl Glutathione Glycine Guanylate cyclase Gut flora HMBS (gene)Hans Fischer Heme A Heme B Heme C Heme O Heme a Heme b Heme c Heme o Heme oxygenase Heme oxygenase-1 Heme peroxidase Hemoglobin Hemoprotein Hemoproteins Hereditary coproporphyria Histidine Homeostasis Hydroxymethylbilane Hypobromite IUPAC Impossible Foods Inborn error of metabolism Inversely proportional Ion Iron Isobacteriochlorin Kidney Lactoperoxidase Leghemoglobin Ligand Ligand (biochemistry)Lipoic acid Liver Living organisms Macrocycle Magnesium Magnesium protoporphyrin Malaria Manganese Meat analogue Metabolic intermediate Metalloprotein Methanofuran Methyl Methylcobalamin MicroRNA Mineral (nutrient)Mitochondria Mitochondrion Molecule Molybdenum Molybdopterin Mycofactocin Myeloperoxidase Myoglobin NAD(P)H NADPH Neutrophil Nickel Nicotinamide adenine dinucleotide Nicotinamide adenine dinucleotide phosphate Nitric oxide Nitrosamine formation during digestion Oxidase Oxidative metabolism Oxidative stress Oxygen PH PPOX Peroxidase Peroxide Pheophytin Pheophytin a Pheophytin b Phosphate Photosynthesis Phycobilin Phycocyanobilin Phycoerythrobilin Phycourobilin Phycoviolobilin Phytobilin Phytochromobilin Phytomenadione Phytoporphyrin Pichia pastoris Pigment Porphobilinogen Porphyria cutanea tarda Porphyrin Porphyrinogen Programmed cell death Propionic acid Prosthetic group Protein Data Bank Protochlorophyllide Protoporphyrin Protoporphyrin IX Protoporphyrinogen IX Pseudovitamin B12 Pterobilin Pyridoxal phosphate Pyrrole Pyrroloquinoline quinone Redox S-Adenosyl methionine Sepsis Serum albumin Siroheme Sirohydrochlorin Space-filling model Spirolactone Spleen Stercobilin Stercobilinogen Steric Succinate dehydrogenase Succinyl-CoA Sulfonamides Sulfur Synthase Tetradentate ligand Tetrahydrobiopterin Tetrahydrofolic acid Tetrahydromethanopterin Tetrapyrrole Thiamine pyrophosphate Thyroid peroxidase Tissue (biology)Transition metal porphyrin complexes UROD UROS Uridine diphosphate glucuronic acid Uridine monophosphate Urine Urobilin Urobilinogen Uroporphyrinogen Uroporphyrinogen I Uroporphyrinogen III Variegate porphyria Veganism Vinyl group Vitamin Vitamin B12 Vitamin C Vitamin K Xenobiotic Zinc Zinc protoporphyrin Δ-aminolevulinic acid

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