Definition
Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels, formed in the earlier stage of vasculogenesis. Angiogenesis continues the growth of the vasculature mainly by processes of sprouting and splitting, but processes such as coalescent angiogenesis, vessel elongation and vessel cooption also play a role. Vasculogenesis is the embryonic formation of endothelial cells from mesoderm cell precursors, and from neovascularization, although discussions are not always precise. The first vessels in the developing embryo form through vasculogenesis, after which angiogenesis is responsible for most, if not all, blood vessel growth during development and in disease.
Related concepts
AC133Aerobic exerciseAlpha-5 beta-1Alpha-v beta-3Alpha-v beta-5Alzheimer's diseaseAmerican Journal of Physiology. Cell PhysiologyAnatomical terminologyAng1Ang2AngioblastAngiogenesis (journal)Angiogenesis inhibitorAngiogeninAngiopoietinsAnnual Review of Cell and Developmental BiologyAnterior cardinal veinAortaAortic archesAortic sacAorticopulmonary septumArteriogenesisAtrioventricular canalBFGFBasement membraneBenign tumorBilayerBlood islandsBlood vesselBlood vesselsBulbus cordisCCL2CD31COX-2CancerCapillariesCardiovascular diseasesCell growthCell junctionCell signalingChemometrics (journal)ChemotherapyChorionCirculating tumor cellCirculatory systemCoalescent angiogenesisCollagenCollagen, type IV, alpha 1Common cardinal veinsConcentrationConnecting stalkDLL4Developmental DynamicsDiet (nutrition)Dorsal aortaDrug resistanceDuctus arteriosusDuctus venosusEdemaEmbryoEmbryogenesisEndocardial cushionsEndoglinEndothelialEndothelial cellEndothelial cellsEndotheliumEndurance exerciseEnzymeEphrinEuropean Journal of PharmacologyExtracellular matrixFGF-1FGF-2Fetal circulationFibroblast growth factorFibrosisForamen ovale (heart)Foramen secundumGene knockoutGene therapyGlycosaminoglycanGranulation tissueGrowth factorGrowth factorsHaematopoiesisHeartHeart developmentHeart diseaseHistamineHyperaemiaHypoxia (medical)ID1ID3 (gene)ImmunogenicityInferior vena cavaInflammationIntegrinIntussusceptive angiogenesisIschemiaJohn Hunter (surgeon)Journal of Cellular PhysiologyJudah FolkmanJunctional moleculeLumen (anatomy)Lymph sacsLymphangiogenesisLymphocyteMRNAMacular degenerationMaggot therapyMalignantMalignant tumorMatrix (biology)Matrix macromoleculesMatrix metalloproteinaseMechanism of actionMedical Subject HeadingsMedicationMesodermMetastasisMicrocirculationMorgan & Claypool publishingMutationMyofibroblastNRP-1National Center for Biotechnology InformationNeonatalNeovascularizationNeuroangiogenesisNeuropilinNihNitric oxideNitric oxide synthaseNotch family of receptorsNova Science PublishersOncogenesisOxygenPDGFRPerforatedPerfusionPericytePhosphorylationPlacentaPlasminogen activatorPlasminogen activator inhibitor-1Platelet-derived growth factorPlatelet derived growth factorPosterior cardinal veinPresentation (medical)Primary interatrial foramenPrimary interventricular foramenPrimitive atriumPrimitive ventricleProteaseProteases in angiogenesisProtein replacement therapyProtein signalling in heart developmentProteinaseProteolysisProteolyticPulmonary arteryReceptor (biochemistry)RetinaSan Rafael, CaliforniaScarSemaphorinSeminars in Cell & Developmental BiologySeptum intermediumSeptum primumSeptum secundumShear stressSinus venosusSmooth muscle cellSpaceSpringer International PublishingSpringer Science & Business MediaStem cellTandemThe Angiogenesis FoundationTie-1Tie-2TimeTransdifferentiationTransforming growth factor betaTransforming growth factor beta receptorTruncus arteriosusTubular heartTumorTyrosine kinasesUmbilical arteryUmbilical cordUmbilical veinUnited States GovernmentUnited States National Library of MedicineVE-cadherinVEGFVEGF-AVEGFRVascular endothelial growth factorVascular remodelling in the embryoVasculatureVasculogenesisVasculogenic mimicryVitelline arteriesVitelline veinsWestern worldWound healingYolk sac
14 concepts already in your glossary